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# Pfizer-BioNTech COVID-19 vaccine clinical trial
- URL: https://www.whiteroseintelligence.com/pfizer-biontech-covid-19-vaccine-clinical-trial/
- Published: 2026-02-20T19:44:00.000Z
- Updated: 2026-02-20T19:44:42.000Z
- Author: Liam Sturgess
- Tags: Profiles, #docs, #clinicaltrial, COVID-19, Clinical Trial, #toc

The [Pfizer-BioNTech COVID-19 vaccine](https://www.whiteroseintelligence.com/Pfizer-BioNTech-COVID-19-vaccine) candidates were tested in a **three-phase clinical trial** in 2020, registered on ClinicalTrials.gov with identifying number C4591001.[\[1\]](#fn1)

## Investigators

The list of investigators was published as a [Supplementary Appendix](https://web.archive.org/web/20230826041437/https://www.medrxiv.org/content/medrxiv/early/2021/07/28/2021.07.28.21261159/DC1/embed/media-1.pdf).[\[2\]](#fn2)

### Trial sites

There were 169 official clinical trial sites listed on the trial's [ClinicalTrials.gov listing](https://web.archive.org/web/20230420203001/https://clinicaltrials.gov/ct2/show/NCT04368728).[\[1:1\]](#fn1) Organizations that served as clinical trial sites included:

- Acevedo Clinical Research Associates
- [AMR Mobile](https://www.whiteroseintelligence.com/AMR-Mobile)
- Anaheim Clinical Trials (ACT)
- Bayview Research Group (BRG)
- California Research Foundation (CRF)
- [Chinle Comprehensive Health Care Facility](https://www.whiteroseintelligence.com/Chinle-Comprehensive-Health-Care-Facility)
- Clinical and Translational Science Center (CTSC)
- Clinical Research Consortium (CRC)
- Clinical Research Consulting (CRC)
- Clinical Research of South Florida
- CNS Healthcare
- Collaborative Neuroscience Research (CNS)
- DeLand Clinical Research Unit
- Diablo Clinical Research
- Fleming Island Center for Clinical Research
- Hope Research Institute
- Indago Research and Health Center
- Jacksonville Center for Clinical Research
- [Johns Hopkins Center for American Indian Health](https://www.whiteroseintelligence.com/Johns-Hopkins-Center-for-Indigenous-Health)
- Kaiser Permanente Los Angeles Medical Center
- Kaiser Permanente Northern California
- Kaiser Permanente Santa Clara
- Long Beach Clinical Trials
- Lynn Institute of Denver
- [Medical Affiliated Research Center](https://www.whiteroseintelligence.com/Medical-Affiliated-Research-Center)
- National Research Institute
- [North Alabama Research Center](https://www.whiteroseintelligence.com/North-Alabama-Research-Center)
- [The Pain Center of Arizona](https://www.whiteroseintelligence.com/Pain-Center-of-Arizona)
- Paradigm Clinical Research
- Providence Clinical Research
- Research Centers of America
- UC Davis Medical Center
- Whiteriver Indian Hospital
- Yale Center for Clinical Investigation

## External links

- [ClinicalTrials.gov](https://web.archive.org/web/20230420203001/https://clinicaltrials.gov/ct2/show/NCT04368728)

---

1. BioNTech SE, & Pfizer. (2023, February 28). *Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals.* ClinicalTrials.gov. <https://web.archive.org/web/20230420203001/https://clinicaltrials.gov/ct2/show/NCT04368728> [↩︎](#fnref1) [↩︎](#fnref1:1)
2. *Supplementary Appendix* (p. 2). (2021). medRxiv. <https://web.archive.org/web/20230826041437/https://www.medrxiv.org/content/medrxiv/early/2021/07/28/2021.07.28.21261159/DC1/embed/media-1.pdf> [↩︎](#fnref2)